The Indianapolis Colts were the only NFL team to score an upset in Week 6. Surely, we can do better than that in Week 7. Odds via ESPN Bet.

Kansas City Chiefs at San Francisco 49ers (-2)

Chiefs head coach Andy Reid is 21-4 following a bye week, the best mark of any coach in NFL history. If that’s not enough to sway you, consider the 49ers injury report.

Wide receiver Deebo Samuel was limited in practice with a wrist injury this week while teammate Jauan Jennings missed two practices with a hip injury. Running back Jordan Mason is also still dealing with a shoulder injury that put him on the sidelines for much of last week’s game against the Seattle Seahawks.

All three are listed as questionable for Sunday’s Super Bowl LVIII rematch. At the moment, only Kansas City’s JuJu Smith-Schuster carries a questionable tag for his team. Smith-Schuster logged a full practice on Wednesday before popping up on the injury report with a hamstring injury.

Only the Baltimore Ravens gain more yards per game (453.7) than the 49ers (420.0) but the undefeated Super Bowl champions still have a top-10 defense and appear to have the 49ers’ number with four straight wins (including a pair of Super Bowls) in their last four meetings.

Detroit Lions at Minnesota Vikings (-1.5)

Did oddsmakers miss Detroit’s 38-point victory over the Dallas Cowboys last weekend? While the Vikings had a week off following a 23-17 victory over the New York Jets in London, the Lions were busy putting up 492 yards and 47 points on “America’s Team.”





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